CD19 抗体 (PE)
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- 抗原 See all CD19 抗体
- CD19 (CD19 Molecule (CD19))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD19 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- Supplier Product No.
- 200-508-m72
- Supplier
- Rockland
- 原理
- CD19 Phycoerythrin Antibody
- 交叉反应 (详细)
- Reactivity is observed against mouse CD19.
- 纯化方法
- Phycoerythrin conjugated CD19 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against mouse CD19.
- 过滤
- Sterile filtered
- 免疫原
- Anti-CD19 Antibody (Monoclonal) was produced by repeated immunizations with mouse CD19 transfected cell line.
- 克隆位点
- 1D3
- 亚型
- IgG2a kappa
- Labeling Ratio
- 1-2
- Top Product
- Discover our top product CD19 Primary Antibody
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- 应用备注
- Optional[Neutralization_Dilution]: 0.25-1 μg/10^6 cells
- 说明
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Anti-CD19 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.1 % Gelatin
Preservative: 0.09 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
- 有效期
- 6 months
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- 抗原
- CD19 (CD19 Molecule (CD19))
- 别名
- CD19 (CD19 产品)
- 背景
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Synonyms: B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19
Background: CD19 is a member of the immunoglobulin superfamily with 556 amino acid and two immunoglobulin-like C2-type domains. As a cell surface protein, CD19 is known to form a complex with CD21, CD81 and CD225 in the membrane of mature B cells. A major function of CD100 is to assemble with the antigen receptor of B lymphocytes so as to decrease the threshold for antigen receptor dependent stimulation thus enhancing the specificity and sensitivity of B cells towards antigens. Thus CD19 is an important protein for B cell antigen receptor signaling and regulation and also acts as a specialized adaptor protein for the amplification of Src family needed for this purpose. Regulation of growth of B cells is a major function of CD19 and its expression is confined to only B lymphocytes and follicular dendritic cells of the hematopoietic system. Increased expression of CD19 induces the production of auto-antibody thus giving an insight to the regulatory role of CD19 in autoimmunity. Defects in CD19 are a cause of hypogammaglobulinemia.
Gene Name: Cd19
- 基因ID
- 12478
- NCBI登录号
- NP_033974
- UniProt
- P25918
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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