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CD19 抗体 (PE)

Rockland 200-508-m72 CD19 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 1D3 PE
Rockland
产品编号 ABIN6657888
Supplier Product No.: 200-508-m72
发货至: 中国
  • 抗原 See all CD19 抗体
    CD19 (CD19 Molecule (CD19))
    适用
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    小鼠
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CD19 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    Supplier Product No.
    200-508-m72
    Supplier
    Rockland
    原理
    CD19 Phycoerythrin Antibody
    交叉反应 (详细)
    Reactivity is observed against mouse CD19.
    纯化方法
    Phycoerythrin conjugated CD19 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against mouse CD19.
    过滤
    Sterile filtered
    免疫原
    Anti-CD19 Antibody (Monoclonal) was produced by repeated immunizations with mouse CD19 transfected cell line.
    克隆位点
    1D3
    亚型
    IgG2a kappa
    Labeling Ratio
    1-2
    Top Product
    Discover our top product CD19 Primary Antibody
  • 应用备注
    Optional[Neutralization_Dilution]: 0.25-1 μg/10^6 cells
    说明

    Anti-CD19 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.1 % Gelatin

    Preservative: 0.09 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
    有效期
    6 months
  • 抗原
    CD19 (CD19 Molecule (CD19))
    别名
    CD19 (CD19 产品)
    背景

    Synonyms: B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19

    Background: CD19 is a member of the immunoglobulin superfamily with 556 amino acid and two immunoglobulin-like C2-type domains. As a cell surface protein, CD19 is known to form a complex with CD21, CD81 and CD225 in the membrane of mature B cells. A major function of CD100 is to assemble with the antigen receptor of B lymphocytes so as to decrease the threshold for antigen receptor dependent stimulation thus enhancing the specificity and sensitivity of B cells towards antigens. Thus CD19 is an important protein for B cell antigen receptor signaling and regulation and also acts as a specialized adaptor protein for the amplification of Src family needed for this purpose. Regulation of growth of B cells is a major function of CD19 and its expression is confined to only B lymphocytes and follicular dendritic cells of the hematopoietic system. Increased expression of CD19 induces the production of auto-antibody thus giving an insight to the regulatory role of CD19 in autoimmunity. Defects in CD19 are a cause of hypogammaglobulinemia.

    Gene Name: Cd19

    基因ID
    12478
    NCBI登录号
    NP_033974
    UniProt
    P25918
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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