ASCL2 抗体 (C-Term)
-
- 抗原 See all ASCL2 抗体
- ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))
-
抗原表位
- C-Term
-
适用
- 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ASCL2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)
- 交叉反应 (详细)
- Cross reactivity with Ash2 from other species not tested.
- 纯化方法
- Anti-Ash2 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
- 免疫原
-
Immunogen: Anti-Ash2 Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Ash2: two containing an amino acid sequence from the internal and one containing an amino acid sequence from the C-terminal part of the protein.
Immunogen Type: Peptide
-
-
- 应用备注
-
Application Note: Anti-Ash2 Antibody is suitable for ELISA, Immunofluorescence and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 68 kDa in the appropriate cell lysate or extract.
ELISA Dilution: 1:100 - 1:500
Western Blot Dilution: 1:1,000
IF Microscopy Dilution: 1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
0.01 % (w/v) Sodium Azide
Stabilizer: None
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
- 抗原
- ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))
- 别名
- Ash2 (ASCL2 产品)
- 别名
- ASH2 antibody, HASH2 antibody, MASH2 antibody, bHLHa45 antibody, ASCL2 antibody, 2410083I15Rik antibody, Mash2 antibody, achaete-scute family bHLH transcription factor 2 antibody, ASCL2 antibody, Ascl2 antibody
- 背景
-
Synonyms: Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L1, ASH2L2, Bre2
Background: Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia. Anti-Ash2 Antibody is ideal for research in Gene Expression, Epigenetics, Cell Signaling and Cancer.
Gene Name: ASH2L
- 基因ID
- 9070
- NCBI登录号
- NP_001098684
- UniProt
- Q9UBL3
- 途径
- Stem Cell Maintenance
-