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ASCL2 抗体 (C-Term)

ASCL2 适用: 小鼠 WB, ELISA, FM 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6657882
发货至: 中国
  • 抗原 See all ASCL2 抗体
    ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))
    抗原表位
    • 15
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 58
    • 39
    • 27
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 56
    • 4
    • 1
    克隆类型
    • 56
    • 5
    多克隆
    标记
    • 25
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASCL2 antibody is un-conjugated
    应用范围
    • 32
    • 15
    • 13
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)
    交叉反应 (详细)
    Cross reactivity with Ash2 from other species not tested.
    纯化方法
    Anti-Ash2 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
    免疫原

    Immunogen: Anti-Ash2 Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Ash2: two containing an amino acid sequence from the internal and one containing an amino acid sequence from the C-terminal part of the protein.

    Immunogen Type: Peptide

  • 应用备注

    Application Note: Anti-Ash2 Antibody is suitable for ELISA, Immunofluorescence and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 68 kDa in the appropriate cell lysate or extract.

    ELISA Dilution: 1:100 - 1:500

    Western Blot Dilution: 1:1,000

    IF Microscopy Dilution: 1:200

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    0.01 % (w/v) Sodium Azide

    Stabilizer: None

    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • 抗原
    ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))
    别名
    Ash2 (ASCL2 产品)
    别名
    ASH2 antibody, HASH2 antibody, MASH2 antibody, bHLHa45 antibody, ASCL2 antibody, 2410083I15Rik antibody, Mash2 antibody, achaete-scute family bHLH transcription factor 2 antibody, ASCL2 antibody, Ascl2 antibody
    背景

    Synonyms: Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L1, ASH2L2, Bre2

    Background: Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia. Anti-Ash2 Antibody is ideal for research in Gene Expression, Epigenetics, Cell Signaling and Cancer.

    Gene Name: ASH2L

    基因ID
    9070
    NCBI登录号
    NP_001098684
    UniProt
    Q9UBL3
    途径
    Stem Cell Maintenance
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