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CD3 epsilon 抗体 (FITC)

Rockland 200-b02-m69 CD3E 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 145-2C11 FITC
Rockland
产品编号 ABIN6657857
Supplier Product No.: 200-b02-m69
发货至: 中国
  • 抗原 See all CD3 epsilon (CD3E) 抗体
    CD3 epsilon (CD3E)
    适用
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    仓鼠
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    标记
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    This CD3 epsilon antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    Supplier Product No.
    200-b02-m69
    Supplier
    Rockland
    原理
    CD3e Fluorescein Antibody
    交叉反应 (详细)
    Reactivity is observed against mouse CD3.
    纯化方法
    Fluorescein conjugated CD3 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against mouse CD3.
    过滤
    Sterile filtered
    免疫原
    Anti-CD3 Antibody (Monoclonal) was produced by repeated immunizations with H-2Kb specific cytotoxic T lymphocyte clone BM10-37.
    克隆位点
    145-2C11
    亚型
    IgG
    Labeling Ratio
    2-8
    Top Product
    Discover our top product CD3E Primary Antibody
  • 应用备注

    Flow_Cytometry_Dilution: 0.1-0.5 μg/10^6 cells

    Other: Sufficient to run approximately 500 tests

    说明

    Anti-CD3 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.1 % Gelatin

    Preservative: 0.09 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.
    有效期
    6 months
  • 抗原
    CD3 epsilon (CD3E)
    别名
    CD3e (CD3E 产品)
    背景

    Synonyms: T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e

    Background: CD3 is a multi-subunit complex consisting of 4 different invariable membrane proteins, CD3E, CD3D, CD3G and CD3-omega. These CD3 proteins are expressed on the surface of T-cells and Thymocytes during thymocyte development. They are non-covalently associated with the TCR heterodimer and form the functional TCR-CD3 antigen receptor complex of the T-lymphocyte. CD3 expression is significant during Intrathymic T-lymphocyte maturation, TCR signaling and Thymocyte differentiation. Stimulation of TCR-CD3 complex results in activation of various protein tyrosine kinases including ZAP-70 affecting multiple cellular responses including T-cell proliferation, clonal expansion, induction of tolerance and apoptosis. Mutations in the sub-unit chains of CD3 have been associated with various immunodeficiency syndromes including SCID.

    Gene Name: Cd3e

    基因ID
    12501
    NCBI登录号
    NP_031674
    UniProt
    P22646
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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