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CD11b 抗体 (PE)

ITGAM 适用: 小鼠 FACS, IHC, IP, FM 宿主: 大鼠 Monoclonal M1-70 PE
产品编号 ABIN6657853
发货至: 中国
  • 抗原 See all CD11b (ITGAM) 抗体
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
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    大鼠
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    This CD11b antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
    交叉反应 (详细)
    Cross reactivity Human, Chimpanzee, Baboon, Cynomolgus, Rhesus, Rabbit (Lapine)
    纯化方法
    Phycoerythrin conjugated CD11b Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD11b. . Cross-reactivity with CD11b from other sources has not been tested. Anti-CD11b is conjugated with PE under optimal conditions and the solution is free of unconjugated PE.
    免疫原

    Immunogen: Anti-CD11b Antibody (Monoclonal) was produced by repeated immunizations with CD11b antigen.

    克隆位点
    M1-70
    亚型
    IgG2b
    Labeling Ratio
    1-2
    Top Product
    Discover our top product ITGAM Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: User Optimized

    Application Note: Anti-CD11b is useful for Immunoprecipitation, Immunohistochemistry, and Flow Cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.

    Immunoprecipitation Dilution: User Optimized

    Flow Cytometry Dilution: 10 μL/10^6 cells (0.1 μg)

    IF Microscopy Dilution: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    0.09 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
  • 抗原
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    别名
    CD11b (ITGAM 产品)
    别名
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    背景

    Synonyms: CD11b

    Background: CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

    Gene Name: Itgam

    UniProt
    A1E2I0
    途径
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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