BAT3 抗体 (C-Term)
(2 references)
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- 抗原 See all BAT3 抗体
- BAT3 (Large Proline-Rich Protein BAT3 (BAT3))
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抗原表位
- C-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAT3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- Supplier Product No.
- 100-401-b63s
- Supplier
- Rockland
- 原理
- Scythe/Bat3 Antibody
- 纯化方法
- This product was prepared from monospecific antiserum by addition of Sodium azide to 0.01 % .
- 过滤
- Sterile filtered
- 免疫原
- This Bat3 Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the C-terminal portion of mouse Scythe/Bat3.
- 亚型
- IgG
- Top Product
- Discover our top product BAT3 Primary Antibody
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anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-1126) antibody
BAT3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-1126) antibodyBAT3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 943-992) antibodyBAT3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-200) antibodyBAT3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (Internal Region) antibodyVerified BAT3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-200) antibodyBAT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA_Dilution: User Optimized
Western_Blot_Dilution: 1:5,000 to 1:8,000
- 说明
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This polyclonal antibody has been tested for use in western blotting and is specific for mouse Scythe/Bat3 and its isoforms. Specific conditions for reactivity should be optimized by the end user. Expect multiple bands, with the predominant at approximately 200kDa in size corresponding to Scythe/BAT3 by western blotting in the appropriate cell lysate or extract. In western blot analysis of endogenous protein, multiple bands of Scythe/BAT3 may appear corresponding to variable amount of splice isoforms present.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
- 有效期
- 3 months
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: "Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3264-71, (2008) (PubMed).
: "The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development." in: Molecular and cellular biology, Vol. 25, Issue 23, pp. 10329-37, (2005) (PubMed).
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: "Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3264-71, (2008) (PubMed).
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- 抗原
- BAT3 (Large Proline-Rich Protein BAT3 (BAT3))
- 别名
- Scythe/Bat3 (BAT3 产品)
- 背景
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Synonyms: rabbit anti-Bat3 Antibody, rabbit anti-Scythe Antibody, Bat3, HLA-B-associated transcript 3, Large proline-rich protein BAT3
Background: Scythe protein (also known as Bat3 and HLA-B-associated transcript 3) is an apoptotic regulator that is highly conserved in eukaryotes and contains a ubiquitin-like domain near its N-terminus. Scythe binds Reaper, a potent apoptotic inducer. Scythe and Reaper are thought to signal apoptosis, in part through regulating the folding and and activity of apoptotic signaling molecules. Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis. Scythe interacts with transforming growth factor-beta (TGF-beta) receptors and enhances TGF-beta1-induced type I collagen expression in mesangial cells. Scythe and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression. HLA-B-associated transcript 3 (Bat3/Scythe) is essential for p300-mediated acetylation of p53. Bat3 is identified as a critical regulator of Hsp70-2 in spermatogenesis, thereby providing a possible molecular target in idiopathic male infertility. The human Scythe/BAT3 ortholog in rodents is predominantly and developmentally expressed in testis.
Gene Name: BAT3
- 基因ID
- 224727, 33147082
- UniProt
- Q9Z1R2
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