KCNMB2 抗体 (C-Term, N-Term)
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- 抗原 See all KCNMB2 抗体
- KCNMB2 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 2 (KCNMB2))
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抗原表位
- C-Term, N-Term
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KCNMB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-BK channel BETA2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with BK channel BETA2 from human, mouse, and rat based on 100% homology with the immunizing sequence. Detects endogenous and exogenous hsp22 in monomeric, dimeric and tetrameric forms in WB. Does not cross react with alpha crystallin. Cross-reactivity with BK channel BETA2 from other sources has not been determined. Ion Channels research.
- 免疫原
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Immunogen: BK channel BETA2 Antibody was produced in mice by repeated immunizations with a fusion protein N-terminus and C-terminus regions of mouse BKBeta2.
Immunogen Type: Recombinant Protein
- 克隆位点
- S53-32
- 亚型
- IgG1
- Top Product
- Discover our top product KCNMB2 Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-BK channel Beta3 Antibody is suitable for use in WB, IP, and IHC. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: User Optimized
Western Blot Dilution: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- KCNMB2 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 2 (KCNMB2))
- 别名
- BK channel BETA2 (KCNMB2 产品)
- 别名
- KCNMB3 antibody, zgc:101842 antibody, KCNMB2 antibody, 2700049B16Rik antibody, 3110031N04Rik antibody, Kcmb2 antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 2 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 2 antibody, KCNMB2 antibody, kcnmb2 antibody, Kcnmb2 antibody
- 背景
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Synonyms: KCNMB2, Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, BKbeta2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, K(VCA)beta-2, Maxi K channel subunit beta-2, Slo-beta-2
Background: BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release. A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia. This has major implications on other physiological processes in tissues other than the brain.
Gene Name: Kcnmb2
- 基因ID
- 72413
- NCBI登录号
- NP_082507
- UniProt
- Q9CZM9
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