电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TLR5 抗体

Rockland 200-401-i28 TLR5 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN6656728
Supplier Product No.: 200-401-i28
发货至: 中国
  • 抗原 See all TLR5 抗体
    TLR5 (Toll-Like Receptor 5 (TLR5))
    适用
    • 88
    • 56
    • 27
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 80
    • 15
    • 2
    克隆类型
    • 73
    • 24
    多克隆
    标记
    • 47
    • 11
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR5 antibody is un-conjugated
    应用范围
    • 78
    • 40
    • 31
    • 14
    • 9
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Supplier Product No.
    200-401-i28
    Supplier
    Rockland
    原理
    TLR5 Antibody
    交叉反应 (详细)
    A BLAST analysis was used to suggest cross-reactivity with Anti-TLR5 from human, rat and mouse based on 100 % homology with the immunizing sequence.
    纯化方法
    Anti-TLR5 Antibody was purified by Protein G chromatography.
    免疫原
    TLR5 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a KLH-conjugated peptide corresponding to internal amino acids on human TLR5 protein.
    亚型
    IgG
    Top Product
    Discover our top product TLR5 Primary Antibody
  • 应用备注

    Immunohistochemistry_Dilution: 10 μg/mL (paraffin)

    Flow_Cytometry_Dilution: 1-2 μg/10^6 cells

    Western_Blot_Dilution: 1-3 μg/mL

    说明

    Anti-TLR5 Antibody is tested for use in WB, Flow, Flow-CS, IHC, and IHC-P. Expect a band approximately 97kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.05 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    TLR5 (Toll-Like Receptor 5 (TLR5))
    别名
    TLR5 (TLR5 产品)
    背景

    Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3

    Background: Anti-TLR5 Antibody detects human TLR5. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Thirteen homologs of TLRs (TLR1-13) have been described. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens. Anti-TLR5 Antibody is ideal for investigator involved in cytokine and growth factor research.

    Gene Name: TLR5

    基因ID
    7100
    NCBI登录号
    NP_003259
    UniProt
    O60602
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
You are here:
客服