TLR5 抗体
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- 抗原 See all TLR5 抗体
- TLR5 (Toll-Like Receptor 5 (TLR5))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TLR5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-TLR5 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR5 from human, rat and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR5 from other sources has not been determined.
- 免疫原
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Immunogen: TLR5 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a KLH-conjugated peptide corresponding to internal amino acids on human TLR5 protein.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product TLR5 Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: 10 μg/mL (paraffin)
Application Note: Anti-TLR5 Antibody is suitable for use in Flow (I), IHC (p) and WB. Expect a band approximately 97 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Flow Cytometry Dilution: 1-2 μg/10^6 cells
Western Blot Dilution: 1-3 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.20.05 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- TLR5 (Toll-Like Receptor 5 (TLR5))
- 别名
- TLR5 (TLR5 产品)
- 别名
- SLEB1 antibody, TIL3 antibody, TLR-5 antibody, sleb1 antibody, til3 antibody, tlr-5 antibody, tlr5 antibody, toll like receptor 5 antibody, toll-like receptor 5 antibody, toll like receptor 5 L homeolog antibody, toll-like receptor 5b antibody, TLR5 antibody, Tlr5 antibody, tlr5.L antibody, tlr-5 antibody, tlr5b antibody
- 背景
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Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3
Background: Anti-TLR5 Antibody detects human TLR5. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Thirteen homologs of TLRs (TLR1-13) have been described. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens. Anti-TLR5 Antibody is ideal for investigator involved in cytokine and growth factor research.
Gene Name: TLR5
- 基因ID
- 7100
- NCBI登录号
- NP_003259
- UniProt
- O60602
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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