CNTNAP2 抗体 (Extracellular Domain)
-
- 抗原 See all CNTNAP2 抗体
- CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
-
抗原表位
- Extracellular Domain
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CNTNAP2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- Supplier Product No.
- 200-301-f04
- Supplier
- Rockland
- 原理
- CASPR2 Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with CASPR2 from Mouse, Human, and Rat based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-CASPR2 Antibody was purified by Protein G chromatography.
- 过滤
- Sterile filtered
- 免疫原
- CASPR2 Antibody was produced in mice by repeated immunizations with a fusion protein (extracellular domain) of human CASPR2.
- 克隆位点
- S67-25
- 亚型
- IgG2a
- Top Product
- Discover our top product CNTNAP2 Primary Antibody
-
-
- 应用备注
-
Immunoprecipitation_Dilution: User Optimized
Immunohistochemistry_Dilution: 0.1-1.0 μg/mL
IF_Microscopy_Dilution: 1.0-10 μg/mL
Western_Blot_Dilution: 1 μg/mL
- 说明
-
Anti-CASPR2 Antibody is tested in WB, IP, and IHC. Expect a band approximately ~180kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Buffer: 1X PBS, pH 7.4
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.09 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
-
- 抗原
- CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
- 别名
- CASPR2 (CNTNAP2 产品)
- 背景
-
Synonyms: Cntnap2, CNTP2, Contactin associated protein like 2, Cell recognition molecule Caspr2, CASPR2, KIAA0868
Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.
Gene Name: CNTNAP2
- 基因ID
- 26047
- NCBI登录号
- NP_054860
- UniProt
- Q9UHC6
-