CNTNAP2 抗体 (Extracellular Domain)
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- 抗原 See all CNTNAP2 抗体
- CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
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抗原表位
- Extracellular Domain
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CNTNAP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-CASPR2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CASPR2 from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. No cross reactivity to CASPR/Paranodin. Cross-reactivity with CASPR2 from other sources has not been determined. Scaffolds research.
- 免疫原
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Immunogen: CASPR2 Antibody was produced in mice by repeated immunizations with a fusion protein (extracellular domain) of human CASPR2.
Immunogen Type: Recombinant Protein
- 克隆位点
- S67-25
- 亚型
- IgG2a
- Top Product
- Discover our top product CNTNAP2 Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-CASPR2 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~180 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: User Optimized
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 1X PBS, pH 7.4
Stabilizer: 50 % (v/v) Glycerol
0.09 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
- 别名
- CASPR2 (CNTNAP2 产品)
- 别名
- AUTS15 antibody, CASPR2 antibody, CDFE antibody, NRXN4 antibody, PTHSL1 antibody, 5430425M22Rik antibody, Caspr2 antibody, mKIAA0868 antibody, CASPR antibody, MGC145769 antibody, MGC147944 antibody, MGC147981 antibody, contactin associated protein like 2 antibody, contactin associated protein-like 2 antibody, contactin associated protein like 2b antibody, CNTNAP2 antibody, Cntnap2 antibody, cntnap2b antibody, cntnap2 antibody
- 背景
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Synonyms: Cntnap2, CNTP2, Contactin associated protein like 2, Cell recognition molecule Caspr2, CASPR2, KIAA0868
Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.
Gene Name: CNTNAP2
- 基因ID
- 26047
- NCBI登录号
- NP_054860
- UniProt
- Q9UHC6
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