Reticulon 4 抗体
-
- 抗原 See all Reticulon 4 (RTN4) 抗体
- Reticulon 4 (RTN4)
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Reticulon 4 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)
- Supplier Product No.
- 100-401-h97
- Supplier
- Rockland
- 原理
- Nogo-A B Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with Anti-Nogo-A B from human, mouse, and rat based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-Nogo A/B Antibody is sera.
- 免疫原
- Nogo-A/B Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic sequence corresponding to internal Nogo-A human protein.
- 亚型
- IgG
- Top Product
- Discover our top product RTN4 Primary Antibody
-
-
- 应用备注
-
ELISA_Dilution: User Optimized
Immunohistochemistry_Dilution: 1:100
IF_Microscopy_Dilution: User Optimized
Western_Blot_Dilution: 1:500-1:2000
- 说明
-
Anti-Nogo A/B Antibody has been tested by WB, ELISA, ICC/IF, IHC, IHC-P. Expect a band approximately 48-50kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store Nogo A B antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
-
- 抗原
- Reticulon 4 (RTN4)
- 别名
- Nogo-A B (RTN4 产品)
- 背景
-
Synonyms: KIAA0886, NOGO, Reticulon-4, Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, NSP, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5
Background: Nogo B 1/2 is a novel myelin-associated, intermediate-length splice variant of Nogo belonging to the reticulon family. It is a multi domain neurite growth inhibitory protein containing several discrete regions with growth inhibitory functions and is a component of the CNS myelin that prevents axonal regeneration in the adult vertebrate CNS. Nogo B1/2 along with NGBR mediated chemotaxis in HUVECs and induced tube formation in 3-dimensional cultures. It is mostly found in intact blood vessels, smooth muscle cells, and endothelial cell, with its N-terminus oriented extracellularly and is a regulator of vascular homeostasis and remodeling. It plays an important role in sporadic and familial amyotrophic lateral sclerosis. Anti-Nogo A/B is ideal for researchers interested in Neurobiology research.
Gene Name: RTN4
- 基因ID
- 57142
- NCBI登录号
- NP_008939
- UniProt
- Q9NQC3
- 途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
-