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GFAP 抗体 (AA 411-422) (Biotin)

Name: GFAP 抗体 (AA 411-422) (Biotin)
SKU: ABIN6656176
Availability: OutOfStock

GFAP 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal S206B-9 Biotin

产品编号 ABIN6656176

发货至: 中国

Datasheet as PDF

抗原 See all GFAP 抗体

GFAP (Glial Fibrillary Acidic Protein (GFAP))
抗原表位
33

27

20

16

12

9

9

8

8

7

7

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 411-422
适用
289

172

170

51

51

34

31

11

11

10

7

6

5

4

3

2

2

2

1

1

1

1
人
宿主
186

144

12

2

2

2
小鼠
Compatible Secondaries
克隆类型
190

158
单克隆
标记
164

27

24

17

12

7

6

4

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1
This GFAP antibody is conjugated to Biotin
应用范围
272

130

93

80

73

58

47

28

26

26

22

19

13

8

8

4

4

3

2

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

原理

GFAP R416WT Antibody Biotin

交叉反应（详细）

A BLAST analysis was used to suggest cross-reactivity with rat and mouse based on 100 % homology with the immunizing sequence.

纯化方法

Anti-GFAP R416WT Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

过滤

Sterile filtered

免疫原

Anti-GFAP R416WT Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to amino acids 411-422 (KTVEMRDGEVIK) of human GFAP.

克隆位点

S206B-9

亚型

IgG1

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anti-Glial Fibrillary Acidic Protein (GFAP) (C-Term) antibody
Verified GFAP 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Glial Fibrillary Acidic Protein (GFAP) antibody
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应用备注

ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: User Optimized
Western_Blot_Dilution: 1:1000

说明

Anti-GFAP R416WT Biotin Conjugated Antibody is suitable for use in Western blot, Immunohistochemistry, and Immunocytochemistry. Expect a band approximately ~50 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

限制

仅限研究用
状态

Liquid

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

12 months
抗原

GFAP (Glial Fibrillary Acidic Protein (GFAP))

别名

GFAP (GFAP 产品)

别名

GFAP antibody, AI836096 antibody, cb345 antibody, etID36982.3 antibody, gfapl antibody, wu:fb34h11 antibody, wu:fk42c12 antibody, xx:af506734 antibody, zgc:110485 antibody, glial fibrillary acidic protein antibody, GFAP antibody, LOC100136168 antibody, gfap antibody, Gfap antibody

背景

Synonyms: Glial fibrillary acidic protein, Intermediate filament protein, Astrocyte, gfapl, DKFZp459C0729, MGC139638, FLJ45472, AI836096, GFAP antibody
Background: The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. Anti-GFAP is ideal for investigators involved in Neuroscience Research, including Alexander Disease, Oligodendroglioma, Cytoskleton Remolding Neurofilaments and PIP3/AKT Signaling.
Gene Name: GFAP

基因ID

2670

UniProt

P14136