KDELR1 抗体
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- 抗原 See all KDELR1 抗体
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDELR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Supplier Product No.
- 600-401-f85
- Supplier
- Rockland
- 原理
- KDEL Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with KDEL from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-KDEL Antibody was purified by affinity chromatography.
- 过滤
- Sterile filtered
- 免疫原
- KDEL Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against KDEL containing synthetic peptide immunogen.
- 亚型
- IgG
- Top Product
- Discover our top product KDELR1 Primary Antibody
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- 应用备注
- Optional[Neutralization_Dilution]: 1:1000
- 说明
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Anti-KDEL Antibody is tested for use in WB, IF, and IHC. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
- 别名
- KDELR1 (KDELR1 产品)
- 背景
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Synonyms: Lys Asp Glu Leu, K-D-E-L, ER lumen protein retaining receptor 1, KDEL endoplasmic reticulum protein retention, Kdelr1
Background: The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER.
Gene Name: Kdelr1
- 基因ID
- 10945
- NCBI登录号
- NP_006792
- UniProt
- P24390
- 途径
- Maintenance of Protein Location
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