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Aquaporin 4 抗体 (C-Term)

Rockland 600-401-e92 AQP4 适用: 大鼠 WB, IHC, IF, FM 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN6656113
Supplier Product No.: 600-401-e92
发货至: 中国
  • 抗原 See all Aquaporin 4 (AQP4) 抗体
    Aquaporin 4 (AQP4)
    抗原表位
    • 20
    • 16
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 69
    • 62
    • 61
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 78
    • 18
    • 1
    克隆类型
    • 76
    • 21
    多克隆
    标记
    • 47
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aquaporin 4 antibody is un-conjugated
    应用范围
    • 72
    • 46
    • 26
    • 24
    • 22
    • 15
    • 14
    • 14
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)
    Supplier Product No.
    600-401-e92
    Supplier
    Rockland
    原理
    Aquaporin 4 Antibody
    交叉反应 (详细)
    A BLAST analysis was used to suggest cross-reactivity with Aquaporin 4 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.
    纯化方法
    Anti-Aquaporin 4 Antibody was purified by affinity chromatography.
    过滤
    Sterile filtered
    免疫原
    Aquaporin 4 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of rat aquaporin 4.
    亚型
    IgG
    Top Product
    Discover our top product AQP4 Primary Antibody
  • 应用备注

    IF_Microscopy_Dilution: 1:400

    Western_Blot_Dilution: 1:1000-4000

    说明

    Anti-Aquaporin 4 Antibody is tested for use in WB, IHC, and IF microscopy. Expect a band approximately ~35kDa on specific lysates. May detect larger glycosylated bands ~50kDa. Specific conditions for reactivity should be optimized by the end user.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.1 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    Aquaporin 4 (AQP4)
    别名
    Aquaporin 4 (AQP4 产品)
    背景

    Synonyms: AQP4, Aquaporin-4, Mercurial-insensitive water channel, MIWC, WCH4

    Background: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins. Aquaporin 4 is constitutively expressed in the basolateral cell membrane of princinpal collecting duct cells in the kidney and provide a pathway for water to exit these cells. It is also expressed in astrocytes and is upregulated by direct insult to the CNS. Aquaporin 4 has been propsed as the primary autoimmune target in neuromyelitis optica.

    Gene Name: Aqp4

    基因ID
    25293
    NCBI登录号
    NP_036957
    UniProt
    P47863
    途径
    Sensory Perception of Sound
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