Aquaporin 4 抗体 (C-Term)
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- 抗原 See all Aquaporin 4 (AQP4) 抗体
- Aquaporin 4 (AQP4)
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抗原表位
- C-Term
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aquaporin 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)
- Supplier Product No.
- 600-401-e92
- Supplier
- Rockland
- 原理
- Aquaporin 4 Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with Aquaporin 4 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-Aquaporin 4 Antibody was purified by affinity chromatography.
- 过滤
- Sterile filtered
- 免疫原
- Aquaporin 4 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of rat aquaporin 4.
- 亚型
- IgG
- Top Product
- Discover our top product AQP4 Primary Antibody
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- 应用备注
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IF_Microscopy_Dilution: 1:400
Western_Blot_Dilution: 1:1000-4000
- 说明
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Anti-Aquaporin 4 Antibody is tested for use in WB, IHC, and IF microscopy. Expect a band approximately ~35kDa on specific lysates. May detect larger glycosylated bands ~50kDa. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- Aquaporin 4 (AQP4)
- 别名
- Aquaporin 4 (AQP4 产品)
- 背景
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Synonyms: AQP4, Aquaporin-4, Mercurial-insensitive water channel, MIWC, WCH4
Background: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins. Aquaporin 4 is constitutively expressed in the basolateral cell membrane of princinpal collecting duct cells in the kidney and provide a pathway for water to exit these cells. It is also expressed in astrocytes and is upregulated by direct insult to the CNS. Aquaporin 4 has been propsed as the primary autoimmune target in neuromyelitis optica.
Gene Name: Aqp4
- 基因ID
- 25293
- NCBI登录号
- NP_036957
- UniProt
- P47863
- 途径
- Sensory Perception of Sound
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