DUX4 抗体 (C-Term)
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- 抗原 See all DUX4 抗体
- DUX4 (Double Homeobox 4 (DUX4))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DUX4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
- 纯化方法
- Anti-DUX4 Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for human DUX4 protein. A BLAST analysis was used to suggest cross-reactivity with DUX4 from human based on 100% homology with the immunizing sequence. It does not cross react with DUX4c. Cross-reactivity with DUX4 from other sources has not been determined. Transcription Factor research.
- 免疫原
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Immunogen: DUX4 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to the C-terminal region of human DUX4 protein.
Immunogen Type: Peptide
- 克隆位点
- P2B1
- 亚型
- IgG1
- Top Product
- Discover our top product DUX4 Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-DUX4 Antibody is suitable for use in WB, IF, and IHC. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1:1000
IF Microscopy Dilution: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- DUX4 (Double Homeobox 4 (DUX4))
- 别名
- DUX4 (DUX4 产品)
- 别名
- DUX4 antibody, DUX4L antibody, double homeobox, 4 antibody, double homeobox 4 antibody, DUX4 antibody
- 背景
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Synonyms: mouse anti-DUX4 Antibody, double homeobox 4, DUX4, Double homeobox protein 4-like protein, DUX4L2, DUX4L3, DUX4L5, DUX4L6, DUX4L7
Background: DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcipt is not completely suppressed in skeletal muscle and possibly other differentiated tissues.
Gene Name: DUX2
- 基因ID
- 22947
- NCBI登录号
- NP_149418
- UniProt
- F5GZ66
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