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TLR7 抗体

Rockland 200-301-i29 TLR7 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal IMG4G6 unconjugated
Rockland
产品编号 ABIN6655379
Supplier Product No.: 200-301-i29
发货至: 中国
  • 抗原 See all TLR7 抗体
    TLR7 (Toll-Like Receptor 7 (TLR7))
    适用
    • 87
    • 42
    • 9
    • 3
    • 3
    • 3
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    • 1
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    • 1
    • 1
    宿主
    • 84
    • 17
    小鼠
    克隆类型
    • 74
    • 26
    • 1
    单克隆
    标记
    • 56
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
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    This TLR7 antibody is un-conjugated
    应用范围
    • 55
    • 44
    • 23
    • 15
    • 15
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Supplier Product No.
    200-301-i29
    Supplier
    Rockland
    原理
    TLR7 Antibody
    交叉反应 (详细)
    A BLAST analysis was used to suggest cross-reactivity with Anti-TLR7 from human based on 100 % homology with the immunizing sequence.
    纯化方法
    Anti-TLR7 Antibody was purified by Protein G chromatography.
    免疫原
    TLR7 Antibody was produced in mice prepared by repeated immunizations with an internal portion of human TLR7 recombinant protein.
    克隆位点
    IMG4G6
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TLR7 Primary Antibody
  • 应用备注

    Flow_Cytometry_Dilution: 1-2 μg/10^6 cells

    Western_Blot_Dilution: 10 μg/mL

    说明

    Anti-TLR7 Antibody is tested for use in WB, Flow, Flow-IC, ICC/IF, and IHC. Expect a band approximately 121kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    Preservative: 0.05 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    TLR7 (Toll-Like Receptor 7 (TLR7))
    别名
    TLR7 (TLR7 产品)
    背景

    Synonyms: Toll-like receptor 7

    Background: Anti-TLR7 Antibody detects human TLR7. TLR7 is a 1049 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain. It plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV). It is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8. It acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Anti-TLR7 Antibody is ideal for investigators that are involved in cytokin and grow factor research.

    Gene Name: TLR7

    基因ID
    51284
    NCBI登录号
    NP_057646
    UniProt
    Q9NYK1
    途径
    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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