TRF2 抗体
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- 抗原 See all TRF2 (TERF2) 抗体
- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TRF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Flow Cytometry (FACS), Fluorescence Microscopy (FM)
- 原理
- TRF2 Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with Anti-TRF2 from Human, Mouse, Muntjac (deer), and rat based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-TRF2 Antibody was purified by Protein G chromatography.
- 免疫原
- TRF2 Antibody was produced in mice by repeated immunizations with a full-length TRF2 human protein.
- 克隆位点
- 4A794-15
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TERF2 Primary Antibody
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- 应用备注
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ChIP_Dilution: User Optimized
Immunoprecipitation_Dilution: 2 μg/10^6 cells
ELISA_Dilution: 2 μg/mL
Immunohistochemistry_Dilution: 5 μg/mL
Flow_Cytometry_Dilution: User Optimized
IF_Microscopy_Dilution: User Optimized
Western_Blot_Dilution: 2-4 μg/mL
- 说明
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Anti-TRF2 Antibody is tested for use in WB, ChIP, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, and IP. Expect a band approximately 55.6 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
- 别名
- TERF2 (TERF2 产品)
- 别名
- TERF2 antibody, TRBF2 antibody, TRF2 antibody, trf2 antibody, telomeric repeat binding factor 2 antibody, telomeric repeat binding factor 2 L homeolog antibody, TERF2 antibody, Terf2 antibody, terf2.L antibody
- 背景
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Synonyms: TRBF2, TRF2, Telomeric repeat-binding factor 2, TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein
Background: TRF2 antibody detects human, mouse, deer and rat TRF2. TRF2 is an ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types. Anti TRF2 antibody is ideal for investigators involved in apoptosis and chromatin research.
Gene Name: TERF2
- 基因ID
- 7014
- NCBI登录号
- NP_005643
- UniProt
- Q15554
- 途径
- Cell Division Cycle, Telomere Maintenance
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