CD8 alpha 抗体 (FITC)
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- 抗原 See all CD8 alpha (CD8A) 抗体
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD8 alpha antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- Supplier Product No.
- 200-302-m64
- Supplier
- Rockland
- 原理
- CD8 Fluorescein Antibody
- 交叉反应 (详细)
- Reactivity is observed against human CD8 and chimpanzee.
- 纯化方法
- Fluorescein conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8.
- 过滤
- Sterile filtered
- 免疫原
- Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
- 克隆位点
- RPA-T8
- 亚型
- IgG1 kappa
- Labeling Ratio
- 2-8
- Top Product
- Discover our top product CD8A Primary Antibody
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- 应用备注
- Optional[Neutralization_Dilution]: 10 μL/10^6 cells (0.25 μg)
- 说明
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Anti-CD8 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.1 % Gelatin
Preservative: 0.09 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store vial at 4° C prior to opening. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. DO NOT FREEZE. This product is light sensitive.
- 有效期
- 6 months
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- 抗原
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- 别名
- CD8A (CD8A 产品)
- 背景
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Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL
Background: CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.
Gene Name: CD8
- 基因ID
- 925
- NCBI登录号
- NP_001139345
- UniProt
- P01732
- 途径
- TCR Signaling
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