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CD8 alpha 抗体 (FITC)

Rockland 200-302-m64 CD8A 适用: 人 FACS 宿主: 小鼠 Monoclonal RPA-T8 FITC
Rockland
产品编号 ABIN6655185
Supplier Product No.: 200-302-m64
发货至: 中国
  • 抗原 See all CD8 alpha (CD8A) 抗体
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD8 alpha antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    Supplier Product No.
    200-302-m64
    Supplier
    Rockland
    原理
    CD8 Fluorescein Antibody
    交叉反应 (详细)
    Reactivity is observed against human CD8 and chimpanzee.
    纯化方法
    Fluorescein conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8.
    过滤
    Sterile filtered
    免疫原
    Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
    克隆位点
    RPA-T8
    亚型
    IgG1 kappa
    Labeling Ratio
    2-8
    Top Product
    Discover our top product CD8A Primary Antibody
  • 应用备注
    Optional[Neutralization_Dilution]: 10 μL/10^6 cells (0.25 μg)
    说明

    Anti-CD8 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.1 % Gelatin

    Preservative: 0.09 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.
    有效期
    6 months
  • 抗原
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    别名
    CD8A (CD8A 产品)
    背景

    Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL

    Background: CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.

    Gene Name: CD8

    基因ID
    925
    NCBI登录号
    NP_001139345
    UniProt
    P01732
    途径
    TCR Signaling
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