ABCA4 抗体
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- 抗原 See all ABCA4 抗体
- ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
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适用
- Cow
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ABCA4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 牛, 人, 小鼠, 非洲爪蟾
- 纯化方法
- Anti-ABCA4 antibody is directed against bovine ABCA4 Rim Protein. The antibody was Protein G purified from culture supernatant. Reactivity is expected against human, mouse and Xenopus. Cross-reactivity with ABCA4 from other sources has not been determined.
- 免疫原
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Immunogen: Anti-ABCA4 antibody was produced by repeated immunizations with partially purified bovine 220-kDa disc rim protein.
Immunogen Type: Native Protein
- 克隆位点
- 3F4
- 亚型
- IgG
- Top Product
- Discover our top product ABCA4 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 2250-2263) antibody
Verified ABCA4 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 1398-1727) antibodyABCA4 适用: 人 WB, ELISA, IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) antibodyABCA4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 2174-2273) antibodyABCA4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (C-Term) antibodyABCA4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) antibodyABCA4 适用: Cow WB, IHC 宿主: 小鼠 Monoclonal 3F4 unconjugated
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- 应用备注
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Immunohistochemistry Dilution: 1:100
Application Note: Anti-ABCA4 antibody is suitable for use in ELISA, Western Blotting and IHC. Specific conditions should be optimized by the end user. Expect a band of ~220 kDa in size corresponding to ABCA4 proteins in the appropriate cell lysate or extract.
ELISA Dilution: 1:10,000
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- 抗原
- ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
- 别名
- ABCA4 Rim Protein (ABCA4 产品)
- 别名
- ABC10 antibody, ABCR antibody, ARMD2 antibody, CORD3 antibody, FFM antibody, RMP antibody, RP19 antibody, STGD antibody, STGD1 antibody, AW050280 antibody, Abc10 antibody, Abcr antibody, D430003I15Rik antibody, RmP antibody, abcr antibody, ffm antibody, rmp antibody, rp19 antibody, stgd antibody, abc10 antibody, armd2 antibody, cord3 antibody, stgd1 antibody, zgc:91823 antibody, ATP binding cassette subfamily A member 4 antibody, ATP-binding cassette, sub-family A (ABC1), member 4 antibody, ATP binding cassette subfamily A member 4 L homeolog antibody, ATP-binding cassette, sub-family A (ABC1), member 4a antibody, ABCA4 antibody, Abca4 antibody, abca4 antibody, abca4.L antibody, abca4a antibody
- 背景
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Synonyms: Retinal-specific ATP-binding cassette transporter, ATP-binding cassette sub-family A member 4, RIM ABC transporter
Background: ABCA4 antibody detects ABCA4 (ATP-binding cassette, sub-family A (ABC1), member 4, Rim Protein) a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABCA4 is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essential molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and age-related macular degeneration. Defects in ABCA4 are the cause of Stargardt disease type 1 (STGD1). STGD is one of the most frequent causes of macular degeneration in childhood. Defects in ABCA4 are also known to cause fundus flavimaculatus (FFM), age-related macular degeneration type 2 (ARMD2) and cone-rod dystrophy type 3 (CORD3). Anti-ABCA4 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: ABCA4
- 基因ID
- 11304
- NCBI登录号
- NP_776646
- UniProt
- O35600
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