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- 抗原 See all MMP2 抗体
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MMP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- 免疫原
- This MMP2 antibody is generated from mouse immunized with MMP2 recombinant protein.
- 克隆位点
- 6E3F8
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product MMP2 Primary Antibody
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- 应用备注
- WB: 1:200~1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze-thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma." in: Oncogene, Vol. 37, Issue 8, pp. 1086-1094, (2018) (PubMed).
: "The CD147/MMP-2 signaling pathway may regulate early stage cardiac remodelling in spontaneously hypertensive rats." in: Clinical and experimental pharmacology & physiology, Vol. 43, Issue 11, pp. 1125-1133, (2017) (PubMed).
: "Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax." in: The Kaohsiung journal of medical sciences, Vol. 33, Issue 1, pp. 17-23, (2017) (PubMed).
: "EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway." in: Oncotarget, Vol. 6, Issue 16, pp. 14191-208, (2016) (PubMed).
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DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma." in: Oncogene, Vol. 37, Issue 8, pp. 1086-1094, (2018) (PubMed).
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- 抗原
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- 别名
- MMP2 (MMP2 产品)
- 别名
- 2-MMP antibody, CG1794 antibody, DM2-MMP antibody, Dm2-MMP antibody, Dmel\\CG1794 antibody, MMP2 antibody, anon-WO0118547.84 antibody, dm-2MMP antibody, dmmp2 antibody, l(2)02353 antibody, mmp2 antibody, wu:fa99h12 antibody, wu:fk89d01 antibody, fgmmp-2 antibody, Mmp-2 antibody, LOC100135793 antibody, Clg4a antibody, GelA antibody, MMP-2 antibody, CLG4 antibody, CLG4A antibody, MMP-II antibody, MONA antibody, TBE-1 antibody, matrix metallopeptidase 2 antibody, Matrix metalloproteinase 2 antibody, matrix metalloproteinase 2 antibody, matrix metalloproteinase-2 antibody, MMP2 antibody, Mmp2 antibody, mmp2 antibody, LOC657982 antibody, LOC100135793 antibody
- 背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 73882
- 基因ID
- 4313
- NCBI登录号
- NP_001121363, NP_004521
- UniProt
- P08253
- 途径
- Activation of Innate immune Response
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