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Dystroglycan 抗体 (C-Term)

Name: Dystroglycan 抗体 (C-Term)
SKU: ABIN658022
Availability: OutOfStock

DAG1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33752 unconjugated

All lanes : Anti-DAG1 Antibody (C-term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: SH-SY5Y whole cell lysate Lysates/proteins at 20 μg per lane. (Dystroglycan 抗体 (C-Term))

DAG1 Antibody (C-term) ((ABIN658022 and ABIN2846960))immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. (Dystroglycan 抗体 (C-Term))

IHC (p)

All lanes : Anti-DAG1 Antibody (C-term) at 1:2000 dilution Lane 1: SH-SY5Y whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. (Dystroglycan 抗体 (C-Term))

All lanes : Anti-DAG1 Antibody (C-term) at 1:1000-1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. (Dystroglycan 抗体 (C-Term))

Anti-DAG1 Antibody (C-term) at 1:1000 dilution + NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. (Dystroglycan 抗体 (C-Term))

5 images

产品编号 ABIN658022

发货至: 中国

Datasheet as PDF

抗原 See all Dystroglycan (DAG1) 抗体

Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))
抗原表位
15

11

9

4

1

1

1

1

1

1

1

1

1
AA 718-747, C-Term
适用
30

20

14

5

4

3

2

2

2

2

2

2

1

1

1
人, 小鼠
宿主
43

4

2

1
兔
Compatible Secondaries
克隆类型
46

4
多克隆
标记
22

5

4

4

2

2

1

1

1

1

1

1

1

1

1

1

1
This Dystroglycan antibody is un-conjugated
应用范围
44

23

21

13

13

7

5

5

4

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

Pig, Rb

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This DAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 amino acids from the C-terminal region of human DAG1.

克隆位点

RB33752

亚型

Ig Fraction

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anti-Dystroglycan 1 (DAG1) (AA 28-406) antibody
DAG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (AA 31-140) antibody
DAG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A3 unconjugated

anti-Dystroglycan 1 (DAG1) (Internal Region) antibody
Verified DAG1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (AA 726-744) antibody
DAG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (C-Term) antibody
DAG1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (AA 323-372) antibody
DAG1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 猴, Bat, 小鸡, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (AA 721-770) antibody
DAG1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, 豚鼠, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (C-Term) antibody
DAG1 适用: 人 IHC, IHC (fro) 宿主: 小鼠 Monoclonal 43DAG1-8D5 unconjugated

anti-Dystroglycan 1 (DAG1) (AA 654-749) antibody
DAG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:2000. WB: 1:2000. WB: 1:1000-1:2000. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

DAG1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

有效期

6 months
抗原

Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

别名

DAG1 (DAG1 产品)

别名

LOC398500 antibody, dag1 antibody, MGC53537 antibody, 156DAG antibody, A3a antibody, AGRNR antibody, DAG antibody, MDDGC7 antibody, MDDGC9 antibody, DAG1 antibody, RAB7 antibody, dg antibody, a3a antibody, dag antibody, agrnr antibody, 156dag antibody, D9Wsu13e antibody, DG antibody, Dp427 antibody, Dp71 antibody, CG18250 antibody, CT41273 antibody, DmDG antibody, Dmel\\CG18250 antibody, atu antibody, dgn antibody, dys antibody, GB14967 antibody, APOJ antibody, CLI antibody, RATTRPM2B antibody, SGP-2 antibody, SGP2 antibody, SP-40 antibody, SP40 antibody, TRPM-2 antibody, TRPM2B antibody, Trpm2 antibody, Trpmb antibody, Ala-1 antibody, H9/25 antibody, Ly-27 antibody, Ly-6 antibody, Ly27 antibody, wu:fb83d06 antibody, wu:fi25f06 antibody, wu:fi37b08 antibody, zgc:109786 antibody, DystroGlycaN antibody, dystroglycan 1 L homeolog antibody, dystroglycan 1 antibody, dystroglycan 1 S homeolog antibody, Dystroglycan antibody, dystroglycan antibody, clusterin antibody, lymphocyte antigen 6 complex antibody, dgn-1 antibody, dag1.L antibody, dgn-2 antibody, dgn-3 antibody, DAG1 antibody, dag1.S antibody, Dag1 antibody, dag1 antibody, Dg antibody, LOC408826 antibody, Clu antibody, Ly6 antibody

背景

Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.

分子量

97441

基因ID

1605

NCBI登录号

NP_001159400, NP_001171105, NP_001171106, NP_001171107, NP_001171108, NP_001171109, NP_001171110, NP_001171111, NP_001171112, NP_001171113, NP_001171114, NP_001171115, NP_004384

UniProt

Q14118

途径

Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus