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RFX5 抗体 (AA 237-266)

RFX5 适用: 人 WB 宿主: 兔 Polyclonal RB33870 unconjugated
产品编号 ABIN657925
发货至: 中国
  • 抗原 See all RFX5 抗体
    RFX5 (Regulatory Factor X 5 (RFX5))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 237-266
    适用
    • 34
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    宿主
    • 31
    • 3
    • 1
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    This RFX5 antibody is un-conjugated
    应用范围
    • 33
    • 20
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This RFX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the Central region of human RFX5.
    克隆位点
    RB33870
    亚型
    Ig Fraction
    Top Product
    Discover our top product RFX5 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    RFX5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    RFX5 (Regulatory Factor X 5 (RFX5))
    别名
    RFX5 (RFX5 产品)
    别名
    regulatory factor X5 antibody, regulatory factor X, 5 (influences HLA class II expression) antibody, RFX5 antibody, Rfx5 antibody
    背景
    A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq].
    分子量
    65323
    基因ID
    5993
    NCBI登录号
    NP_000440, NP_001020774
    UniProt
    P48382
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