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C4B 抗体 (AA 655-684)

C4b 适用: 人 WB 宿主: 兔 Polyclonal RB33642 unconjugated
产品编号 ABIN657906
发货至: 中国
  • 抗原 See all C4B (C4b) 抗体
    C4B (C4b) (Complement Component C4b (C4b))
    抗原表位
    • 15
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 655-684
    适用
    • 43
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 52
    • 4
    • 3
    克隆类型
    • 55
    • 4
    多克隆
    标记
    • 18
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C4B antibody is un-conjugated
    应用范围
    • 26
    • 20
    • 14
    • 13
    • 13
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    H
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This C4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 655-684 amino acids from the Central region of human C4B.
    克隆位点
    RB33642
    亚型
    Ig Fraction
    Top Product
    Discover our top product C4b Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    C4B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    C4B (C4b) (Complement Component C4b (C4b))
    别名
    C4B (C4b 产品)
    背景
    This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.
    分子量
    192785
    基因ID
    721
    NCBI登录号
    NP_001002029, NP_001239133, NP_009224
    UniProt
    P0C0L4
    途径
    Complement System
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