This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This MIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human MIST.
MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603, BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1, MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326], Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).