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Nemo-Like Kinase 抗体 (C-Term)

NLK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34651 unconjugated
产品编号 ABIN657850
发货至: 中国
  • 抗原 See all Nemo-Like Kinase (NLK) 抗体
    Nemo-Like Kinase (NLK)
    抗原表位
    • 15
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 408-436, C-Term
    适用
    • 71
    • 34
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 72
    • 4
    克隆类型
    • 72
    • 4
    多克隆
    标记
    • 26
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Nemo-Like Kinase antibody is un-conjugated
    应用范围
    • 68
    • 31
    • 26
    • 26
    • 19
    • 11
    • 10
    • 10
    • 9
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk.
    克隆位点
    RB34651
    亚型
    Ig Fraction
    Top Product
    Discover our top product NLK Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Mouse Nlk Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    Nemo-Like Kinase (NLK)
    别名
    Nlk (NLK 产品)
    背景
    Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
    分子量
    58313
    基因ID
    100044468, 18099
    NCBI登录号
    NP_032728
    UniProt
    O54949
    途径
    Ubiquitin Proteasome Pathway
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