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HTR2C 抗体 (AA 253-282)

HTR2C 适用: 人 WB 宿主: 兔 Polyclonal RB34033 unconjugated
产品编号 ABIN657817
发货至: 中国
  • 抗原 See all HTR2C 抗体
    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
    抗原表位
    • 15
    • 9
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 253-282
    适用
    • 73
    • 49
    • 42
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    宿主
    • 69
    • 3
    • 1
    克隆类型
    • 62
    • 11
    多克隆
    标记
    • 30
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HTR2C antibody is un-conjugated
    应用范围
    • 56
    • 30
    • 13
    • 13
    • 12
    • 11
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HTR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the Central region of human HTR2C.
    克隆位点
    RB34033
    亚型
    Ig Fraction
    Top Product
    Discover our top product HTR2C Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    HTR2C Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
    别名
    HTR2C (HTR2C 产品)
    别名
    5-HT2C antibody, 5-HTR2C antibody, HTR1C antibody, 5-HT2cR antibody, 5HT1c antibody, Htr1c antibody, SR1 antibody, 5HT-1C antibody, 5HT2C antibody, 5-HT-2C antibody, 5-ht2cr antibody, si:dkey-24g18.2 antibody, 5ht2c antibody, 5HTR2C antibody, 5-hydroxytryptamine receptor 2C antibody, 5-hydroxytryptamine (serotonin) receptor 2C antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody, HTR2C antibody, Htr2c antibody, htr2c.S antibody, htr2cl1 antibody, LOC407134 antibody
    背景
    Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims.
    分子量
    51821
    基因ID
    3358
    NCBI登录号
    NP_000859, NP_001243689, NP_001243690
    UniProt
    P28335
    途径
    Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
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