This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This POC1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 326-360 amino acids from the C-terminal region of human POC1A.
Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation.