Metabotropic Glutamate Receptor 6 抗体 (AA 369-398)
-
- 抗原 See all Metabotropic Glutamate Receptor 6 (GRM6) 抗体
- Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
-
抗原表位
- AA 369-398
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Metabotropic Glutamate Receptor 6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This GRM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the Central region of human GRM6.
- 克隆位点
- RB33716
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GRM6 Primary Antibody
-
-
- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- GRM6 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
-
- 抗原
- Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
- 别名
- GRM6 (GRM6 产品)
- 背景
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
- 分子量
- 95468
- 基因ID
- 2916
- NCBI登录号
- NP_000834
- UniProt
- O15303
-