MMP16 抗体 (C-Term)
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- 抗原 See all MMP16 抗体
- MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))
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抗原表位
- AA 519-548, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MMP16 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human MMP16.
- 克隆位点
- RB33657
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MMP16 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- MMP16 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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High expression of matrix metalloproteinases 16 is associated with the aggressive malignant behavior and poor survival outcome in colorectal carcinoma." in: Scientific reports, Vol. 7, pp. 46531, (2017) (PubMed).
: "MMP16 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma." in: Oncotarget, Vol. 8, Issue 42, pp. 72197-72204, (2017) (PubMed).
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High expression of matrix metalloproteinases 16 is associated with the aggressive malignant behavior and poor survival outcome in colorectal carcinoma." in: Scientific reports, Vol. 7, pp. 46531, (2017) (PubMed).
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- 抗原
- MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))
- 别名
- MMP16 (MMP16 产品)
- 别名
- MT3-MMP antibody, Mt3mmp antibody, Mt3-mmp antibody, C8orf57 antibody, MMP-X2 antibody, MT-MMP2 antibody, MT-MMP3 antibody, matrix metallopeptidase 16 antibody, Mmp16 antibody, MMP16 antibody
- 背景
- Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
- 分子量
- 69521
- 基因ID
- 4325
- NCBI登录号
- NP_005932
- UniProt
- P51512
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