PCDHGA3 抗体 (AA 284-311)
PCDHgA3
适用: 人
WB, FACS, IHC (p)
宿主: 兔
Polyclonal
RB33029
unconjugated
(1 reference)-
- 抗原 See all PCDHGA3 (PCDHgA3) 抗体
- PCDHGA3 (PCDHgA3) (Protocadherin gamma A3 (PCDHgA3))
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抗原表位
- AA 284-311
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCDHGA3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This PCDHGA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 amino acids from the Central region of human PCDHGA3.
- 克隆位点
- RB33029
- 亚型
- Ig Fraction
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- PCDHGA3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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: "Protocadherin γ A3 is expressed in follicular lymphoma irrespective of BCL2 status and is associated with tumor cell growth." in: Molecular medicine reports, Vol. 14, Issue 5, pp. 4622-4628, (2017) (PubMed).
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: "Protocadherin γ A3 is expressed in follicular lymphoma irrespective of BCL2 status and is associated with tumor cell growth." in: Molecular medicine reports, Vol. 14, Issue 5, pp. 4622-4628, (2017) (PubMed).
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- 抗原
- PCDHGA3 (PCDHgA3) (Protocadherin gamma A3 (PCDHgA3))
- 别名
- PCDHGA3 (PCDHgA3 产品)
- 别名
- PCDH-GAMMA-A3 antibody, protocadherin gamma subfamily A, 3 antibody, PCDHGA3 antibody, Pcdhga3 antibody
- 背景
- This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
- 分子量
- 100971
- 基因ID
- 56112
- NCBI登录号
- NP_061739, NP_114400
- UniProt
- Q9Y5H0
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