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SART1 抗体

SART1 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6571846
发货至: 中国
  • 抗原 See all SART1 抗体
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    适用
    • 32
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 29
    • 2
    • 1
    克隆类型
    • 32
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SART1 antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 13
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human SART1
    亚型
    IgG
    Top Product
    Discover our top product SART1 Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000 IP 1:20 - 1:50
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    别名
    SART1 (SART1 产品)
    别名
    Dmel\\CG6686 antibody, SART1 antibody, MGC53679 antibody, MGC132129 antibody, zgc:91927 antibody, Ara1 antibody, HOMS1 antibody, SART1259 antibody, SNRNP110 antibody, Snu66 antibody, U5-110K antibody, CG6686 gene product from transcript CG6686-RB antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 antibody, squamous-cell carcinoma T-cell-recognized antigen antibody, squamous cell carcinoma antigen recognized by T cells 1 antibody, CG6686 antibody, sart1.S antibody, sart1 antibody, SART1 antibody, Sart1 antibody
    背景

    Synonyms: Ara 1,ARA1,HOMS 1,HOMS1,hSART 1,hSART1,hSnu 66,hSnu66,IgE autoantigen,MGC2038,SART 1,SART1 259,SART1(259) protein,SART1(800) protein,SART1259,Snu 66,Snu66 ,Squamous cell carcinoma antigen recognised by T cells,Squamous cell carcinoma antigen recognized by T cells 1,U4/U6.U5 tri snRNP associated 110 kDa protein ,U4/U6.U5 tri snRNP associated protein 1

    Background: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

    分子量

    Observed_MW: 120kDa

    Calculated_MW: 90kDa

    基因ID
    9092
    UniProt
    O43290
    途径
    Ribonucleoprotein Complex Subunit Organization
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