XPC 抗体
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- 抗原 See all XPC 抗体
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XPC antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human XPC (NP_004619.3).
- 亚型
- IgG
- Top Product
- Discover our top product XPC Primary Antibody
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- 应用备注
- IHC 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
- 别名
- XPC (XPC 产品)
- 别名
- RAD4 antibody, XP3 antibody, XPCC antibody, XPC complex subunit, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group C antibody, XPC antibody, Xpc antibody
- 背景
- This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
- 分子量
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Observed_MW: 130kDa
Calculated_MW: 15kDa/101kDa/105kDa
- 基因ID
- 7508
- UniProt
- Q01831
- 途径
- p53 Pathway, DNA Damage Repair
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