RENT2/UPF2 抗体
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- 抗原 See all RENT2/UPF2 (UPF2) 抗体
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RENT2/UPF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human UPF2
- 亚型
- IgG
- Top Product
- Discover our top product UPF2 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
- 别名
- UPF2 (UPF2 产品)
- 别名
- HUPF2 antibody, RENT2 antibody, smg-3 antibody, UPF2, regulator of nonsense mediated mRNA decay antibody, UPF2 regulator of nonsense transcripts homolog (yeast) antibody, UPF2 antibody, Upf2 antibody, upf2 antibody
- 背景
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Synonyms: DKFZp434D222,hUpf2,KIAA1408,MGC138834,MGC138835,Nonsense mRNA reducing factor 2,Regulator of nonsense transcripts 2,RENT2,RENT2,Smg 3,Smg 3 homolog nonsense mediated mRNA decay factor,Up-frameshift suppressor 2 homolog,UPF2,UPF2 regulator of nonsense transcripts homolog,UROC1,Urocanate hydratase,Yeast Upf2p homolog
Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.
- 分子量
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Observed_MW: 148kDa
Calculated_MW: 66kDa/147kDa
- 基因ID
- 26019
- UniProt
- Q9HAU5
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