ANTXR1 抗体
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- 抗原 See all ANTXR1 抗体
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANTXR1 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human ANTXR1 (NP_060623.2).
- 亚型
- IgG
- Top Product
- Discover our top product ANTXR1 Primary Antibody
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- 应用备注
- IF 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- 别名
- ANTXR1 (ANTXR1 产品)
- 别名
- ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody
- 背景
- This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
- 分子量
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Observed_MW: 75kDa
Calculated_MW: 33kDa/37kDa/39kDa/41kDa/59kDa/62kDa
- 基因ID
- 84168
- UniProt
- Q9H6X2
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