This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-526 amino acids from the C-terminal region of human SP2.
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.