This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This KAT2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-638 amino acids from the C-terminal region of human KAT2A.
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).