PEX5 抗体
-
- 抗原 See all PEX5 抗体
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PEX5 antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human PEX5 (NP_000310.2).
- 亚型
- IgG
- Top Product
- Discover our top product PEX5 Primary Antibody
-
-
- 应用备注
- IHC 1:50-1:200 IF 1:50-1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
- 别名
- PEX5 (PEX5 产品)
- 别名
- AW212715 antibody, ESTM1 antibody, PTS1R antibody, Pxr1 antibody, X83306 antibody, PTS1-BP antibody, PBD2A antibody, PBD2B antibody, PXR1 antibody, Peroxin-5 antibody, peroxisomal biogenesis factor 5 antibody, pex5 antibody, Pex5 antibody, PEX5 antibody
- 背景
- The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
- 分子量
-
Observed_MW: 70kDa
Calculated_MW: 66kDa/69kDa/70kDa/72kDa
- 基因ID
- 5830
- UniProt
- P50542
- 途径
- Monocarboxylic Acid Catabolic Process
-