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GNAS 抗体 (C-Term)

GNAS 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33001 unconjugated
产品编号 ABIN656989
发货至: 中国
  • 抗原 See all GNAS 抗体
    GNAS (GNAS Complex Locus (GNAS))
    抗原表位
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 287-315, C-Term
    适用
    • 75
    • 29
    • 25
    • 10
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 70
    • 9
    • 1
    克隆类型
    • 72
    • 8
    多克隆
    标记
    • 48
    • 8
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GNAS antibody is un-conjugated
    应用范围
    • 62
    • 39
    • 27
    • 15
    • 14
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M, Rat, B, Ha, Pig
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human GNAS.
    克隆位点
    RB33001
    亚型
    IgG
    Top Product
    Discover our top product GNAS Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    GNAS Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    GNAS (GNAS Complex Locus (GNAS))
    别名
    GNAS (GNAS 产品)
    背景
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
    分子量
    44250
    基因ID
    2778
    UniProt
    Q5FWY2
    途径
    Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
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