PHD1 抗体
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- 抗原 See all PHD1 (EGLN2) 抗体
- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human EGLN2
- 亚型
- IgG
- Top Product
- Discover our top product EGLN2 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000 IP 1:20 - 1:50
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
- 别名
- EGLN2 (EGLN2 产品)
- 背景
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Synonyms: DKFZp434E026,EGL nine (C.elegans) homolog 2,Egl nine homolog 2 (C. elegans),Egl nine homolog 2,EGLN 2,EGLN2,EGLN2,EIT 6,EIT6,Estrogen-induced tag 6,HIF P4H 1,HIF PH1,HIF prolyl hydroxylase 1,HIF-PH1,HIF-prolyl hydroxylase 1,HIFPH 1,HIFPH1,HPH 3,HPH-1,HPH-3,HPH3,Hypoxia inducible factor prolyl hydroxylase 1,Hypoxia-inducible factor prolyl hydroxylase 1,P4H1,PHD 1,PhD1,prolyl hydroxylase domain containing protein 1,Prolyl hydroxylase domain-containing protein 1
Background: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.
- 分子量
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Observed_MW: 55kDa
Calculated_MW: 40kDa/43kDa
- 基因ID
- 112398
- UniProt
- Q96KS0
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis
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