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GRIA4 抗体 (AA 296-325)

Name: GRIA4 抗体 (AA 296-325)
SKU: ABIN656865
Availability: OutOfStock

GRIA4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30232 unconjugated

Anti-GRIA4 Antibody (Center) at 1:1000 dilution + human brain lysate Lysates/proteins at 20 μg per lane. (GRIA4 抗体 (AA 296-325))

GRIA4 Antibody (Center) (ABIN656865 and ABIN2846069) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (GRIA4 抗体 (AA 296-325))

IHC (p)

GRIA4 Antibody (Center) (ABIN656865 and ABIN2846069) western blot analysis in mouse spleen tissue lysates (35 μg/lane). (GRIA4 抗体 (AA 296-325))

3 images

(1 reference)

产品编号 ABIN656865

发货至: 中国

Datasheet as PDF

抗原 See all GRIA4 抗体

GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
抗原表位
15

15

12

7

7

7

5

5

4

3

2

2

1

1

1

1

1

1

1
AA 296-325
适用
70

49

26

3

3

3

1
人, 小鼠
宿主
71

3
兔
Compatible Secondaries
克隆类型
73

1
多克隆
标记
33

7

6

5

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GRIA4 antibody is un-conjugated
应用范围
61

37

31

13

13

8

4

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

Pr, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This GRIA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human GRIA4.

克隆位点

RB30232

亚型

Ig Fraction

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anti-Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) antibody
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anti-Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Ser433) antibody
GRIA4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) antibody
GRIA4 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Internal Region) antibody (Biotin)
Verified GRIA4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal Biotin

anti-Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (AA 254-433) antibody
GRIA4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

GRIA4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

有效期

6 months
Muntané, Horvath, Hof, Ely, Hopkins, Raghanti, Lewandowski, Wray, Sherwood: "Analysis of synaptic gene expression in the neocortex of primates reveals evolutionary changes in glutamatergic neurotransmission." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 25, Issue 6, pp. 1596-607, (2015) (PubMed).
抗原

GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

别名

GRIA4 (GRIA4 产品)

别名

GLUR4 antibody, GLUR4C antibody, GLURD antibody, GluA4 antibody, GluR4 antibody, GluR4d antibody, GLUR4/D antibody, glur4 antibody, GluR-D antibody, Glur-4 antibody, Glur4 antibody, Gluralpha4 antibody, spkw1 antibody, DKFZp459P0616 antibody, glur4a antibody, gria4 antibody, iGluR4 antibody, ZfGluR4b antibody, fj46g06 antibody, glur4b antibody, wu:fj46g06 antibody, glutamate ionotropic receptor AMPA type subunit 4 antibody, glutamate receptor, ionotropic, AMPA 4 antibody, glutamate receptor, ionotropic, AMPA4 (alpha 4) antibody, glutamate receptor, ionotropic, AMPA 4a antibody, glutamate receptor, ionotropic, AMPA 4b antibody, GRIA4 antibody, gria4 antibody, Gria4 antibody, gria4a antibody, gria4b antibody

背景

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq].

分子量

100871

基因ID

2893

NCBI登录号

NP_000820, NP_001070711, NP_001070712, NP_001106283

UniProt

P48058

途径

PI3K-Akt Signaling