PGK1 抗体
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- 抗原 See all PGK1 抗体
- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PGK1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human PGK1 (NP_000282.1).
- 亚型
- IgG
- Top Product
- Discover our top product PGK1 Primary Antibody
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- 应用备注
- IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
- 别名
- PGK1 (PGK1 产品)
- 别名
- MIG10 antibody, PGKA antibody, Pgk-1 antibody, Pgk antibody, PGK antibody, wu:fd59b07 antibody, wu:fj36g06 antibody, zgc:56252 antibody, zgc:77899 antibody, PGK1 antibody, phosphoglycerate kinase 1 antibody, pgk2 antibody, pgka antibody, phosphoglycerate kinase 1 antibody, phosphoglycerate kinase 1 L homeolog antibody, PGK1 antibody, Pgk1 antibody, pgk1 antibody, LOC100348124 antibody, pgk1.L antibody
- 背景
- The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 41kDa/44kDa
- 基因ID
- 5230
- UniProt
- P00558
- 途径
- Cellular Glucan Metabolic Process
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