TIM3 抗体
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- 抗原 See all TIM3 (TIM 3) 抗体
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIM3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human HAVCR2
- 亚型
- IgG
- Top Product
- Discover our top product TIM 3 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 别名
- HAVCR2 (TIM 3 产品)
- 别名
- HAVCR2 antibody, MGC140131 antibody, HAVcr-2 antibody, KIM-3 antibody, TIM3 antibody, TIMD-3 antibody, TIMD3 antibody, Tim-3 antibody, TIM-3 antibody, Tim3 antibody, Timd3 antibody, tim3 antibody, hepatitis A virus cellular receptor 2 antibody, HAVCR2 antibody, Havcr2 antibody
- 物质类
- Virus
- 背景
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Synonyms: CD366,FLJ14428,HAVcr-2,Havcr2,HAVR2,Hepatitis A virus cellular receptor 2,Kidney injury molecule 3,KIM 3,KIM3,T cell immunoglobulin and mucin domain containing 3,T cell immunoglobulin mucin 3,T-cell immunoglobulin and mucin domain-containing protein 3,T-cell immunoglobulin mucin family member 3,T-cell immunoglobulin mucin receptor 3,T-cell membrane protein 3,Tim 3,TIM-3,TIM3,TIMD-3,TIMD3
Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
- 分子量
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Observed_MW: 35kDa
Calculated_MW: 16kDa/33kDa
- 基因ID
- 84868
- UniProt
- Q8TDQ0
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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