COPS7A 抗体 (C-Term)
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- 抗原 See all COPS7A 抗体
- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
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抗原表位
- AA 237-266, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPS7A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This COPS7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the C-terminal region of human COPS7A.
- 克隆位点
- RB32335
- 亚型
- Ig Fraction
- Top Product
- Discover our top product COPS7A Primary Antibody
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anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 2-275) antibody
COPS7A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 1-275) antibodyCOPS7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 1-275) antibodyCOPS7A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) antibodyCOPS7A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (C-Term) antibodyCOPS7A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (C-Term) antibodyCOPS7A 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (Middle Region) antibodyCOPS7A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 244-274), (C-Term) antibodyCOPS7A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- COPS7A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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- 抗原
- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
- 别名
- COPS7A (COPS7A 产品)
- 别名
- D6Ertd35e antibody, CSN7A antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, Cops7a antibody
- 背景
- Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- 分子量
- 30277
- 基因ID
- 50813
- NCBI登录号
- NP_001157565, NP_001157566, NP_001157567, NP_057403
- UniProt
- Q9UBW8
- 途径
- Cell Division Cycle
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