Spartan 抗体
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- 抗原 See all Spartan (C1orf124) products
- Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Spartan antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human SPRTN
- 亚型
- IgG
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- 应用备注
- WB 1:500 - 1:2000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))
- 别名
- SPRTN (C1orf124 产品)
- 别名
- Spartan antibody, c1orf124 antibody, C1orf124 antibody, DDDL1880 antibody, DVC1 antibody, PRO4323 antibody, dJ876B10.3 antibody, C28H1orf124 antibody, SprT-like N-terminal domain antibody, sprtn antibody, SPRTN antibody
- 背景
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Synonyms: C1orf124,CA124,Chromosome 1 open reading frame 124 ,DDDL1880,dJ876B10.3,PRO4323,RP5-876B10.3,Spartan,SprT-like domain at the N terminus,SprT-like N-terminal domain,Zinc finger RAD18 domain-containing protein C1orf124
Background: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.
- 分子量
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Observed_MW: 60kDa
Calculated_MW: 24kDa/29kDa/55kDa
- 基因ID
- 83932
- UniProt
- Q9H040
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