Fibrillarin 抗体
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- 抗原 See all Fibrillarin (FBL) 抗体
- Fibrillarin (FBL)
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适用
- 人, 小鼠, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Fibrillarin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human FBL
- 亚型
- IgG
- Top Product
- Discover our top product FBL Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Fibrillarin (FBL)
- 别名
- FBL (FBL 产品)
- 背景
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Synonyms: 34 kD nucleolar scleroderma antigen,34 kDa nucleolar scleroderma antigen,Fbl,FBRL,FIB,FIB1,FLRN,Histone-glutamine methyltransferase,Nop1p,RNA U3 small nucleolar interacting protein 1,RNU3IP1,rRNA 2' O methyltransferase fibrillarin,rRNA 2'-O-methyltransferase fibrillarin
Background: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.
- 分子量
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Observed_MW: 36kDa
Calculated_MW: 33kDa
- 基因ID
- 2091
- UniProt
- P22087
- 途径
- Ribonucleoside Biosynthetic Process
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