Aspartate beta Hydroxylase 抗体 (AA 294-323)
-
- 抗原 See all Aspartate beta Hydroxylase (ASPH) 抗体
- Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
-
抗原表位
- AA 294-323
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Aspartate beta Hydroxylase antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ASPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-323 amino acids from the Central region of human ASPH.
- 克隆位点
- RB30223
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ASPH Primary Antibody
-
-
- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- ASPH Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
-
- 抗原
- Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
- 别名
- ASPH (ASPH 产品)
- 别名
- AAH antibody, BAH antibody, CASQ2BP1 antibody, HAAH antibody, JCTN antibody, junctin antibody, 2310005F16Rik antibody, 3110001L23Rik antibody, AI848629 antibody, AW261690 antibody, AW561901 antibody, C79816 antibody, cI-37 antibody, aah antibody, bah antibody, jctn antibody, MGC107896 antibody, cb971 antibody, fb69e10 antibody, fc06d04 antibody, fc95a08 antibody, wu:fb69e10 antibody, wu:fc06d04 antibody, wu:fc95a08 antibody, aspartate beta-hydroxylase antibody, aspartate-beta-hydroxylase antibody, aspartate beta-hydroxylase L homeolog antibody, ASPH antibody, Asph antibody, asph antibody, asph.L antibody
- 背景
- This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.
- 分子量
- 85863
- 基因ID
- 444
- NCBI登录号
- NP_001158222, NP_001158223, NP_001158225, NP_001158227, NP_001158228, NP_004309, NP_064549, NP_115855, NP_115856, NP_115857
- UniProt
- Q12797
- 途径
- Positive Regulation of Endopeptidase Activity
-