Aspartate beta Hydroxylase 抗体 (AA 294-323)
Quick Overview for Aspartate beta Hydroxylase 抗体 (AA 294-323) (ABIN656707)
抗原
See all Aspartate beta Hydroxylase (ASPH) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 294-323
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ASPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-323 amino acids from the Central region of human ASPH.
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亚型
- Ig Fraction
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anti-Aspartate beta-Hydroxylase (ASPH) (AA 345-758) antibody
ASPH 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (AA 75-270) antibodyASPH 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (N-Term) antibodyASPH 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (AA 345-758) antibodyASPH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (AA 1-210) antibodyASPH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (AA 107-156) antibodyASPH 适用: 人, 小鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (AA 161-270) antibodyASPH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (AA 1-270) antibodyASPH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (AA 66-115) antibodyASPH 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aspartate beta-Hydroxylase (ASPH) (Middle Region) antibodyASPH 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- ASPH Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
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别名
- ASPH
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背景
- This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.
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分子量
- 85863
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基因ID
- 444
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NCBI登录号
- NP_001158222, NP_001158223, NP_001158225, NP_001158227, NP_001158228, NP_004309, NP_064549, NP_115855, NP_115856, NP_115857
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UniProt
- Q12797
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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