DVL1 抗体
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- 抗原 See all DVL1 抗体
- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DVL1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human DVL1 (NP_004412.2).
- 亚型
- IgG
- Top Product
- Discover our top product DVL1 Primary Antibody
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- 应用备注
- IHC 1:50-1:200 IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
- 别名
- DVL1 (DVL1 产品)
- 别名
- DVL antibody, DVL1L1 antibody, DVL1P1 antibody, Dvl antibody, mKIAA4029 antibody, dvl-1 antibody, DSH antibody, DVL-1 antibody, dvl1 antibody, dvl2l antibody, Xdsh antibody, dsh1 antibody, dishevelled segment polarity protein 1 antibody, dishevelled, dsh homolog 1 (Drosophila) antibody, microRNA 6808 antibody, dishevelled segment polarity protein 1b antibody, dishevelled segment polarity protein 1 L homeolog antibody, DVL1 antibody, Dvl1 antibody, MIR6808 antibody, dvl1b antibody, dvl1.L antibody
- 背景
- DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
- 分子量
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Observed_MW: 90kDa
Calculated_MW: 72kDa/75kDa
- 基因ID
- 1855
- UniProt
- O14640
- 途径
- WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
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