Desmocollin 1 抗体
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- 抗原 See all Desmocollin 1 (DSC1) 抗体
- Desmocollin 1 (DSC1)
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Desmocollin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human DSC1
- 亚型
- IgG
- Top Product
- Discover our top product DSC1 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Desmocollin 1 (DSC1)
- 别名
- DSC1 (DSC1 产品)
- 别名
- DSC1 antibody, CDHF1 antibody, DG2/DG3 antibody, DSC1b antibody, DG2DG3 antibody, dg3 antibody, Dsc1a antibody, Dsc1b antibody, desmocollin 1 antibody, DSC1 antibody, Dsc1 antibody
- 背景
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Synonyms: Cadherin family member 1,CDHF1,Desmocollin1,Desmosomal glycoprotein 2/3,DG2/DG3,DSC 1,DSC1
Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.
- 分子量
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Observed_MW: 105kDa
Calculated_MW: 93kDa/99kDa
- 基因ID
- 1823
- UniProt
- Q08554
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