Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This STAMBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-383 amino acids from the C-terminal region of human STAMBP.
AMSH antibody, 5330424L14Rik antibody, 5730422L11Rik antibody, AW107289 antibody, Amsh antibody, mKIAA4198 antibody, stambp antibody, zgc:66147 antibody, STAM binding protein antibody, Stam binding protein antibody, STAM binding protein a antibody, STAMBP antibody, Stambp antibody, stambpa antibody
背景
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.