PLOD1 抗体 (N-Term)
(3 references)-
- 抗原 See all PLOD1 抗体
- PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
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抗原表位
- AA 66-94, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLOD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This PLOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human PLOD1.
- 克隆位点
- RB30211
- 亚型
- Ig Fraction
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anti-Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1) (AA 636-727) antibody
PLOD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1) (AA 73-102), (N-Term) antibodyPLOD1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1) (AA 19-114) antibodyPLOD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1) antibodyPLOD1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1) (AA 488-727) antibodyPLOD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. WB: 1:1000-1:2000. WB: 1:2000. IHC-P: 1:25. IHC-P: 1:10~50. FC: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- PLOD1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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: "MBTPS2 mutations cause defective regulated intramembrane proteolysis in X-linked osteogenesis imperfecta. ..." in: Nature communications, Vol. 7, pp. 11920, (2018) (PubMed).
: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).
: "Impaired collagen biosynthesis and cross-linking in aorta of patients with bicuspid aortic valve." in: Journal of the American Heart Association, Vol. 2, Issue 1, pp. e000034, (2013) (PubMed).
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: "MBTPS2 mutations cause defective regulated intramembrane proteolysis in X-linked osteogenesis imperfecta. ..." in: Nature communications, Vol. 7, pp. 11920, (2018) (PubMed).
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- 抗原
- PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
- 别名
- PLOD1 (PLOD1 产品)
- 别名
- EDS6 antibody, LH antibody, LH1 antibody, LLH antibody, PLOD antibody, Plod antibody, procollagen-lysine antibody, 2410042F05Rik antibody, AI854890 antibody, AV007929 antibody, Lh1 antibody, plod1 antibody, ik:tdsubs_rzpd609-29b19 antibody, plod antibody, wu:fc29c10 antibody, wu:fc95g08 antibody, wu:fi18a05 antibody, zgc:152876 antibody, procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 antibody, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 antibody, procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 antibody, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 L homeolog antibody, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a antibody, PLOD1 antibody, Plod1 antibody, PLOD3 antibody, plod1.L antibody, plod1a antibody
- 背景
- Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity.
- 分子量
- 83550
- 基因ID
- 5351
- NCBI登录号
- NP_000293
- UniProt
- Q02809
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