Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
预测反应
Rat
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SLC16A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 433-462 amino acids from the C-terminal region of human SLC16A3.
MCT 3 antibody, MCT 4 antibody, MCT-3 antibody, MCT-4 antibody, MCT3 antibody, MCT4 antibody, mct antibody, slc16a3b antibody, Mct3 antibody, Mct4 antibody, MCT4b antibody, wu:fd20b02 antibody, wu:fi38f12 antibody, zgc:55905 antibody, solute carrier family 16 member 3 antibody, solute carrier family 16 member 3 L homeolog antibody, solute carrier family 16 (monocarboxylic acid transporters), member 3 antibody, solute carrier family 16 (monocarboxylate transporter), member 3 antibody, SLC16A3 antibody, slc16a3.L antibody, Slc16a3 antibody, slc16a3 antibody
背景
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1, MIM 600682) and MCT2 (SLC16A7, MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).