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DVL1 抗体 (AA 442-470)

DVL1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31716 unconjugated
产品编号 ABIN656260
发货至: 中国
  • 抗原 See all DVL1 抗体
    DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
    抗原表位
    • 16
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-470
    适用
    • 48
    • 29
    • 26
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 46
    • 2
    • 2
    克隆类型
    • 50
    多克隆
    标记
    • 19
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DVL1 antibody is un-conjugated
    应用范围
    • 43
    • 19
    • 18
    • 14
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 amino acids from the Central region of human DVL1.
    克隆位点
    RB31716
    亚型
    Ig Fraction
    Top Product
    Discover our top product DVL1 Primary Antibody
  • 应用备注
    IF: 1:10~50. IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Bunn, Daniel, Rösken, ONeill, Cameron-Christie, Morgan, Brunner, Lai, Kunst, Markie, Robertson: "Mutations in DVL1 cause an osteosclerotic form of Robinow syndrome." in: American journal of human genetics, Vol. 96, Issue 4, pp. 623-30, (2015) (PubMed).

  • 抗原
    DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
    别名
    DVL1 (DVL1 产品)
    别名
    DVL antibody, DVL1L1 antibody, DVL1P1 antibody, Dvl antibody, mKIAA4029 antibody, dvl-1 antibody, DSH antibody, DVL-1 antibody, dvl1 antibody, dvl2l antibody, Xdsh antibody, dsh1 antibody, dishevelled segment polarity protein 1 antibody, dishevelled, dsh homolog 1 (Drosophila) antibody, microRNA 6808 antibody, dishevelled segment polarity protein 1b antibody, dishevelled segment polarity protein 1 L homeolog antibody, DVL1 antibody, Dvl1 antibody, MIR6808 antibody, dvl1b antibody, dvl1.L antibody
    背景
    DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
    分子量
    75187
    基因ID
    1855
    NCBI登录号
    NP_004412
    UniProt
    O14640
    途径
    WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
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